| Parameter | Observation | |-----------|--------------| | | EC50 = 8.2 nM (target inhibition) | | Cytotoxicity | Minimal in healthy human fibroblasts (CC50 > 50 µM) | | In vivo efficacy | 65% tumor growth inhibition in xenograft model (50 mg/kg, oral, QD) | | CYP profile | Weak inhibitor of CYP3A4, CYP2D6 | | hERG liability | Negative (IC50 > 30 µM) |
I am not aware of a specific, widely recognized scientific paper or standard document with the identifier in my training data (up to my knowledge cutoff). rexd-541
From available abstracts and conference proceedings (e.g., AACR 2025, SRI 2026): | Parameter | Observation | |-----------|--------------| | |
Common classifications for this title include Cuckold , Married Woman , Big Tits , and 3P/4P (multiple-partner scenes). and 3P/4P (multiple-partner scenes).