Produced by , NALCO 77352 is a proprietary blend of Isothiazolin-3-one biocidal agents. It is primarily used to:
| Endpoint | Finding (based on analog polymers/phosphonates) | |----------|------------------------------------------------| | | LD50 > 2000 mg/kg (practically nontoxic) | | Acute dermal (rabbit) | LD50 > 5000 mg/kg | | Skin irritation | Moderate (rabbit) – erythema at 24h | | Eye irritation | Severe (rabbit) – corneal opacity, iritis; reversible in 7–21 days with treatment | | Sensitization | Not a skin sensitizer (guinea pig maximization test – negative) | | Mutagenicity | Negative (Ames test) | | Reproductive toxicity | No evidence in animal studies with PBTC/polyacrylates | nalco 77352 msds