If you are still struggling, run through this quick checklist:
If you are trying to wake the computer from a (e.g., you are at a coffee shop trying to wake your home PC), your router must be configured to let the signal through. anydesk wake on lan not working
Test with a basic WOL tool from another LAN PC. If that works, blame AnyDesk. If not, fix BIOS/NIC. Then consider whether you actually need AnyDesk WOL or just a better remote power management strategy. If you are still struggling, run through this