Local Anesthetic Metabolism

Local anesthetics undergo metabolism primarily in the liver, where they are broken down into their respective metabolites. The main metabolic pathways involve:

In the quiet of a dental chair or the sterile calm of an operating room, a patient experiences a miracle of modern chemistry: the silence of the nerve. We call it "local anesthesia," a temporary severing of the connection between the body’s sensors and the mind’s awareness. local anesthetic metabolism